Topspec – Next generation precision antibody profiling – from science fiction to reality

Instrumentation:

… to be continued.

Software:

Improved assignment algorithms for antibody spectra that will be used for TopSpec:

C. Gstöttner, D. Reusch, M. Haberger, I. Dragan, P. van Veelen, D.P.A. Kilgour, Y.O. Tsybin, Y.E.M. van der Burgt, M. Wuhrer & S. Nicolardi (2019): Monitoring glycation levels of a bispecific monoclonal antibody at subunit level by ultrahigh resolution MALDI FT-ICR mass spectrometry